Careers

About Imagene

Imagene AI is democratizing precision medicine with multi-modal foundation models and an end-to-end OI Suite. At the core of our technology is a Living Intelligence Engine that continuously integrates and learns from imaging, molecular, and clinical data, making every clinical trial more responsive, every insight more actionable, and every patient journey more personalized.

Our OI Suite is a transformative platform that empowers researchers, clinicians, and pharmaceutical partners across the full spectrum of oncology innovation, from biomarker discovery to patient identification. Our first product, LungOI, is an AI-powered multi-gene test for NSCLC that rapidly profiles biomarkers directly from a standard biopsy image, enabling faster and more informed clinical decisions.

Powered by our state-of-the-art multimodal foundation models- trained on over 1.5 million tissue samples from more than 40 organs and tissue types, along with diverse biological modalities-Imagene AI enables cutting-edge research, especially in data-limited settings.
We are committed to advancing precision medicine and expanding its impact across cancer and beyond. If you are passionate about transforming patient care through AI and innovation, we invite you to join us on this meaningful journey.

Array
← All Jobs

VP of Clinical Development

USA

About The Position

Imagene AI is seeking a pharma-experienced oncology leader to guide the clinical strategy behind our multimodal foundation model and its application across drug development. Our platform integrates histology, DNA, RNA, and routine clinical data to learn each tumor’s response profile and simulate drug-arm outcomes. This enables forecasting of key late-phase metrics and increases confidence in program prioritization and study design.

As the VP of Clinical Development, you will shape how these capabilities support oncology clinical development teams, improve decision making, and optimize trials from concept through execution.

Responsibilities

Pharma Clinical Development Strategy

  • Lead Imagene’s clinical strategy for oncology drug developers, demonstrating how multimodal models inform asset strategy and clinical decision points.
  • Partner with global clinical development and translational teams to align Imagene outputs with asset strategy, indication prioritization, and late-stage planning.

Trial Optimization & Study Design

  • Guide the use of Imagene’s in-silico trial optimization tools.
  • Work directly with clinical science and biostatistics teams to integrate model outputs into trial design.
  • Interpret simulated outcomes alongside real-world variables. 

Evidence Generation & Scientific Rigor

  • Oversee clinical validation strategies using historical trials, retrospective collaborations, and prospective studies with pharma partners.
  • Ensure model-generated signals meet scientific and operational standards expected within oncology development organizations.
  • Lead development of evidence packages.

External Engagement & Scientific Leadership

  • Serve as Imagene’s senior clinical voice with pharma executives, global clinical development leads, and translational oncology heads.
  • Build trusted relationships with oncology KOLs, investigators, cancer centers, and scientific advisors.
  • Represent Imagene at key scientific and industry forums, communicating the clinical value and rigor of the platform.

Regulatory & Strategic Guidance

  • Provide insight into the evolving regulatory landscape for AI-enabled biomarkers, response forecasting, and trial innovation.
  • Support partners in discussions around endpoint justification, population selection, and data packages for regulatory submissions.

Cross-Functional Alignment

  • Collaborate closely with product, ML, science, and business development teams to ensure pharma needs directly shape product evolution.
  • Provide clinical interpretation of multimodal insights and simulation outputs to internal stakeholders and customers.
  • Influence roadmap priorities based on real-world development workflows and unmet needs across oncology programs.

Requirements

  • MD or MD/PhD with oncology training and substantial experience in clinical development within a pharmaceutical or biotech setting.
  • Demonstrated leadership of oncology trials across phases and involvement in asset strategy, study design, and evidence planning.
  • Deep understanding of translational oncology, biomarkers, clinical endpoints, and the decision frameworks used in pharma development.
  • Experience collaborating closely with clinical science, biometrics, regulatory, and translational medicine teams.

Preferred Qualifications:

  • Familiarity with modeling and simulation approaches, advanced analytics, or AI tools used to support trial planning or clinical decision making.
  • Experience with data-driven biomarker strategies or digital biomarker integration.
  • Strong existing network across oncology R&D leadership.


Apply for this position

Get Your Free Access

To submit a case, follow these steps:

  • Send a request email to lab@imagene-ai.com.
  • Provide your name, work email address, and phone number in the email.
  • We will contact you to register an account for the online lab portal.
  • You will receive secured log-in details and a scheduled onboarding call, where we will guide you through the process of submitting a case.
Send Request